A multi-component domino reaction for the direct access to polyfunctionalized indolesvia intermolecular allylic esterification and indolation

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منابع مشابه

A multi-component domino reaction for the direct access to polyfunctionalized indoles via intermolecular allylic esterification and indolation.

A novel multi-component reaction for the synthesis of polyfunctionalized indoles and bis-indoles has been established. The reaction pathways were controlled by varying enamines with different substitution patterns to give polyfunctionalized indoles and bis-indoles selectively. The reaction proceeds at a fast speed within 15-30 min with water as the major byproduct, which makes work-up convenient.

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ژورنال

عنوان ژورنال: Chem. Commun.

سال: 2012

ISSN: 1359-7345,1364-548X

DOI: 10.1039/c1cc15913e